For example, in a group of women with systemic lupus erythematosus, daily doses of DHEA as low as mg improved health-related quality of life and sexual interest and activity compared to placebo. Even more promising are studies suggesting that, in addition to its positive impact on depression and sexual function, DHEA may help to manage symptoms of schizophrenia.
No human study in which DHEA was administered as a supplement or drug has ever shown that it causes cancer. Petri dish and live animal studies show that DHEA may protect against certain cancers. DHEA is produced mainly in the adrenal glands and serves as a natural precursor and balancer to many hormones in the body. In fact, both vitamin D and DHEA are synthesized from cholesterol, the most common sterol found in the body. DHEA has been consistently shown to not influence testosterone levels in young men.
If DHEA did function as an anabolic androgenic steroid, then aging men would not be seeking prescription testosterone drugs to reverse certain symptoms of aging. This is quite an allegation when one considers that DHEA has been freely sold in the United States for over 10 years, with no reports of serious adverse events.
The problem is that members of Congress are not scientists, and they are unable to differentiate between natural steroidal substances in the body such as cholesterol, vitamin D, and DHEA and the synthetic anabolic steroid drugs that are abused by some bodybuilders. Controlled clinical trials indicate that its use in young adults does not result in performance-related gains, and it is not associated with the myriad side effects that accompany anabolic steroid abuse.
Anabolic steroid drug abuse is purported to result in cardiovascular conditions such as hypertension, atherosclerosis, and blood clotting, liver conditions such as jaundice and hepatic carcinoma, tendon damage, reduced fertility and breast enlargement in males , and adverse psychological and behavioral effects.
DHEA does not exert these effects. Moreover, surveys of weightlifters and other athletes conducted by Harvard University researchers show that DHEA is rarely used to increase muscle size or strength or to improve endurance. There is at least one pharmaceutical company lobbyist for each member of Congress.
Drug lobbyists function solely to persuade Congress to enact laws that make pharmaceutical companies more money. Another troublesome aspect about this charade to discredit DHEA is that it could provide a springboard for pharmaceutical companies to attack other supplements that compete against their drug sales. So whether you use DHEA or not, the hoax being perpetrated in Congress is a genuine threat to health freedom across the board.
The companion House bill is H. To register your opposition to these bills, call To write your Senators and Representative, use the form letter on page 35 following the scientific references for this article, or log on to www. The relationship of dehydroepiandrosterone sulfate DHEAS to endocrine-metabolic parameters and functional status in the oldest-old. Results from an Italian study on healthy free-living over-ninety-year-olds.
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Adachi M, Takayanagi R. Role of androgens and DHEA in bone metabolism. Clin Calcium. Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone. J Steroid Biochem Mol Biol. Cancer prevention with dehydroepiandrosterone and non-androgenic structural analogs. J Cell Biochem Suppl. Dehydroepiandrosterone-sulfate inhibits pancreatic carcinoma cell proliferation in vitro and in vivo. Sex-dependent, tissue-specific opposing effects of dehydroepiandrosterone on initiation and modulation stages of liver and lung carcinogenesis induced by dihydroxy-di-n-propylnitrosamine in F rats.
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Dhea supplementation and cognition in postmenopausal women. Health Canada's Upton said the monitoring of online health sales is primarily the responsibility of the provinces, but Ottawa gets involved if there is a violation of federal laws.
But Kruse, at Bad Science Watch, says there is much more that Health Canada can do to protect consumers from unsafe products being sold online by "putting more money into enforcement, by actually having some regulations that have some teeth.
If it is not hard to get banned products from Canadian websites, it is even easier to procure potentially dangerous pills from foreign ones. The fifth estate was able to order two such products from a China-based website and an U. Body Bentonite is a natural health product that is not authorized for sale in Canada and which Health Canada says contains "high levels of metals which may pose serious health risks.
Natural Max Slimming is a natural health product, also not authorized for sale in Canada , which was contaminated or adulterated with potentially dangerous undeclared drugs, according to Health Canada. Pseudonyms will no longer be permitted. By submitting a comment, you accept that CBC has the right to reproduce and publish that comment in whole or in part, in any manner CBC chooses.
Please note that CBC does not endorse the opinions expressed in comments. Comments on this story are moderated according to our Submission Guidelines. Comments are welcome while open. We reserve the right to close comments at any time. Join the conversation Create account. Morales and colleagues studied DHEA in to assess its effects in older individuals.
Thirteen men and 17 women between 40 and 70 years of age took 50 milligrams of DHEA per day for six months. Keep in mind that 13 men and 17 women is not a large sample for "study" purposes.
Study Results Morales and his associates conducted a placebo-controlled, crossover study. In this kind of study, half of the participants received 50 milligrams of DHEA per day, while the other half received an identical-looking placebo pill.
Study participants demonstrated a perceived increase in physical and psychological well-being. Study participants had an increase in the availability of insulin-like growth factor, also known as IGF-I.
This finding suggests that DHEA might be helpful for diabetes mellitus by creating insulin-like properties, and also for increasing muscle mass by creating growth-promoting properties. If DHEA is a predecessor to testosterone, it converts to testosterone in the body, and hence, results in increased testosterone levels and increased muscle mass -- Studies have shown that DHEA does not convert to testosterone, but to dehydrotestosterone, or DHT.
DHT has been shown to cause adverse side effects like irritability, acne, tachycardia and prostate enlargement. These are undesirable side effects that can have serious negative effects on health. DHEA promotes renewed vigor and a sense of well-being -- Although some studies have reported that DHEA may increase feelings of well-being, more studies need to be conducted.
No cause-effect relationship has been established.
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